… study included three prospective cohorts from different ethnicities, which had rigorous study
designs and large sample sizes. Our results were consistent in the three cohorts, indicating …

Background Emerging evidence suggests that there is significant variability in the progression
of frailty in aging. We aimed to identify latent subpopulations of frailty trajectories, and …

… scores that could be calculated at wave 2 of the English Longitudinal Study of Ageing (ELSA),
an observational cohort study. We analysed data from 5,294 participants, 44.9% men, …

… between protein intake and frailty incidence and have obtained … macronutrient intake with
the risk of frailty in older adults. … incident frailty, defined as the presence of at least three of the …

… whether pre-frailty can predict the onset of CVD in a cohort of community-… of incident CVD
in our sample, probably because depression and frailty share the same metabolic changes (ie, …

… Third, there is evidence that the prognosis … cardiovascular risk factors (hypertension and
hyperlipidemia), 12 and we hypothesize that these treatments also could reduce the risk of frailty …

… specific medical conditions, such as cardiovascular disease and … The incident proportions of
frailty and death in this study … Numerous studies have shown that frailty is a risk for mortality.4…

… an inverse cross-sectional association with the metabolic syndrome and insulin resistance
[35], as well as with levels of numerous biomarkers of inflammation and cardiovascular risk [32…

… between cardiovascular risk factors and a frailty score based on the commonly used Fried …
In this cohort of older men, we found an association between frailty—as measured by a novel …

… We conducted cross-sectional and cohort analyses using nationally representative data
from the China Health and Retirement Longitudinal Study (CHARLS). From 2011 to 2018, …